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2jhc
From Proteopedia
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[[Image:2jhc.gif|left|200px]] | [[Image:2jhc.gif|left|200px]] | ||
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'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE''' | '''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE''' | ||
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==Reference== | ==Reference== | ||
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17417654 17417654] | Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17417654 17417654] | ||
| - | [[Category: Bluetongue virus 10 (isolate usa)]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Grimes, J M.]] | [[Category: Grimes, J M.]] | ||
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[[Category: Stuart, D I.]] | [[Category: Stuart, D I.]] | ||
[[Category: Sutton, G.]] | [[Category: Sutton, G.]] | ||
| - | [[Category: | + | [[Category: Core protein]] |
| - | [[Category: | + | [[Category: Guanylyltransferase]] |
| - | [[Category: | + | [[Category: Methyltransferase]] |
| - | [[Category: | + | [[Category: Viral capping enzyme]] |
| - | [[Category: | + | [[Category: Viral protein]] |
| - | [[Category: | + | [[Category: Virion protein]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 08:55:13 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 05:55, 4 May 2008
THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE
Overview
Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.
About this Structure
2JHC is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.
Reference
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654 Page seeded by OCA on Sun May 4 08:55:13 2008
