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2gja

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==Structure of the MnmE G-domain in complex with GDP*AlF4-, Mg2+ and NH4+==
==Structure of the MnmE G-domain in complex with GDP*AlF4-, Mg2+ and NH4+==
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<StructureSection load='2gja' size='340' side='right' caption='[[2gja]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='2gja' size='340' side='right'caption='[[2gja]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2gja]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GJA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GJA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2gja]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GJA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xzp|1xzp]], [[1xzq|1xzq]], [[1rfl|1rfl]], [[2gj8|2gj8]], [[2gj9|2gj9]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xzp|1xzp]], [[1xzq|1xzq]], [[1rfl|1rfl]], [[2gj8|2gj8]], [[2gj9|2gj9]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmE, mnmE, thdF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=469008 ECOBD])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmE, mnmE, thdF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=469008 ECOBD])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gja OCA], [http://pdbe.org/2gja PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gja RCSB], [http://www.ebi.ac.uk/pdbsum/2gja PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gja ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gja OCA], [https://pdbe.org/2gja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gja RCSB], [https://www.ebi.ac.uk/pdbsum/2gja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gja ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MNME_ECOLI MNME_ECOLI]] Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
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[[https://www.uniprot.org/uniprot/MNME_ECOLI MNME_ECOLI]] Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Ecobd]]
[[Category: Ecobd]]
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[[Category: Large Structures]]
[[Category: Scrima, A]]
[[Category: Scrima, A]]
[[Category: Wittinghofer, A]]
[[Category: Wittinghofer, A]]

Revision as of 19:06, 10 March 2021

Structure of the MnmE G-domain in complex with GDP*AlF4-, Mg2+ and NH4+

PDB ID 2gja

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