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2g7c

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==Clostridium difficile Toxin A Fragment Bound to aGal(1,3)bGal(1,4)bGlcNAc==
==Clostridium difficile Toxin A Fragment Bound to aGal(1,3)bGal(1,4)bGlcNAc==
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<StructureSection load='2g7c' size='340' side='right' caption='[[2g7c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2g7c' size='340' side='right'caption='[[2g7c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2g7c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_difficilis"_hall_and_o'toole_1935 "bacillus difficilis" hall and o'toole 1935]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G7C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G7C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2g7c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_difficilis"_hall_and_o'toole_1935 "bacillus difficilis" hall and o'toole 1935]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G7C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G7C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2f6e|2f6e]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2f6e|2f6e]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">toxA, tcdA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1496 "Bacillus difficilis" Hall and O'Toole 1935])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">toxA, tcdA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1496 "Bacillus difficilis" Hall and O'Toole 1935])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g7c OCA], [http://pdbe.org/2g7c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g7c RCSB], [http://www.ebi.ac.uk/pdbsum/2g7c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2g7c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g7c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g7c OCA], [https://pdbe.org/2g7c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g7c RCSB], [https://www.ebi.ac.uk/pdbsum/2g7c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g7c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TOXA_PEPDI TOXA_PEPDI]] Only after the enteral delivery of the enterotoxin A may the characteristic disease called pseudomembranous colitis be induced.
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[[https://www.uniprot.org/uniprot/TOXA_PEPDI TOXA_PEPDI]] Only after the enteral delivery of the enterotoxin A may the characteristic disease called pseudomembranous colitis be induced.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Bacillus difficilis hall and o'toole 1935]]
[[Category: Bacillus difficilis hall and o'toole 1935]]
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[[Category: Large Structures]]
[[Category: Greco, A]]
[[Category: Greco, A]]
[[Category: Ho, J G.S]]
[[Category: Ho, J G.S]]

Revision as of 18:49, 10 March 2021

Clostridium difficile Toxin A Fragment Bound to aGal(1,3)bGal(1,4)bGlcNAc

PDB ID 2g7c

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