This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5xsk
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor== | ==Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor== | ||
| - | <StructureSection load='5xsk' size='340' side='right' caption='[[5xsk]], [[Resolution|resolution]] 2.84Å' scene=''> | + | <StructureSection load='5xsk' size='340' side='right'caption='[[5xsk]], [[Resolution|resolution]] 2.84Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5xsk]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5xsk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21 Escherichia coli BL21] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XSK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XSK FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.84Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xsk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xsk OCA], [https://pdbe.org/5xsk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xsk RCSB], [https://www.ebi.ac.uk/pdbsum/5xsk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xsk ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/HDGF_RAT HDGF_RAT] Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor (By similarity). |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli BL21]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Rattus norvegicus]] |
| - | [[Category: | + | [[Category: Chen CJ]] |
| - | [[Category: | + | [[Category: Chen LY]] |
| - | [[Category: | + | [[Category: Hsieh YC]] |
| - | [[Category: | + | [[Category: Huang YC]] |
| - | [[Category: | + | [[Category: Lin PJ]] |
Current revision
Crystal structure of PWWP-DNA complex for human hepatoma-derived growth factor
| |||||||||||
