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6cxw
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function== | |
| - | + | <StructureSection load='6cxw' size='340' side='right'caption='[[6cxw]], [[Resolution|resolution]] 1.83Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6cxw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CXW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wee|4wee]]</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cxw OCA], [http://pdbe.org/6cxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cxw RCSB], [http://www.ebi.ac.uk/pdbsum/6cxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cxw ProSAT]</span></td></tr> |
| - | [[Category: Sutton, R | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SYT1_RAT SYT1_RAT]] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Sutton, R B]] | ||
| + | [[Category: C2 domain]] | ||
| + | [[Category: Exocytosis]] | ||
Revision as of 05:50, 17 April 2019
Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function
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