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6dtz
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant== | |
| - | + | <StructureSection load='6dtz' size='340' side='right' caption='[[6dtz]], [[Resolution|resolution]] 1.36Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dtz]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DTZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DTZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |
| - | [[ | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6di2|6di2]], [[6di6|6di6]], [[6dtv|6dtv]], [[6du0|6du0]]</td></tr> |
| - | [[Category: Chazin, W | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dtz OCA], [http://pdbe.org/6dtz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dtz RCSB], [http://www.ebi.ac.uk/pdbsum/6dtz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dtz ProSAT]</span></td></tr> |
| - | [[Category: Salay, L | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PRI2_YEAST PRI2_YEAST]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chazin, W J]] | ||
| + | [[Category: Salay, L E]] | ||
| + | [[Category: Dna primase]] | ||
| + | [[Category: Iron-sulfur cluster]] | ||
| + | [[Category: P58]] | ||
| + | [[Category: Regulatory subunit]] | ||
| + | [[Category: Replication]] | ||
Revision as of 06:44, 12 December 2018
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant
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