2kif
From Proteopedia
(Difference between revisions)
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==Solution NMR structure of an O6-methylguanine DNA methyltransferase family protein from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium target VpR247.== | ==Solution NMR structure of an O6-methylguanine DNA methyltransferase family protein from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium target VpR247.== | ||
| - | <StructureSection load='2kif' size='340' side='right' caption='[[2kif]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2kif' size='340' side='right'caption='[[2kif]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kif]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kif]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibpq Vibpq]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KIF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KIF FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">A79_1377, VP0951 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">A79_1377, VP0951 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419109 VIBPQ])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kif OCA], [https://pdbe.org/2kif PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kif RCSB], [https://www.ebi.ac.uk/pdbsum/2kif PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kif ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/A6B4U8_VIBPH A6B4U8_VIBPH]] Involved in DNA damage recognition. Binds DNA containing O(6)-methylguanine (PubMed:20212037). Binds to the damaged base and flips the base out of the DNA duplex into an extrahelical conformation, which allows processing by repair proteins (By similarity).[UniProtKB:P0AFP2]<ref>PMID:20212037</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[DNA methyltransferase|DNA methyltransferase]] | + | *[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Vibpq]] | [[Category: Vibpq]] | ||
[[Category: Acton, T B]] | [[Category: Acton, T B]] | ||
Revision as of 07:26, 14 April 2021
Solution NMR structure of an O6-methylguanine DNA methyltransferase family protein from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium target VpR247.
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Categories: Large Structures | Vibpq | Acton, T B | Aramini, J M | Belote, R L | Ciccosanti, C T | Everett, J K | Jiang, M | Montelione, G T | Structural genomic | Nair, R | Rost, B | Swapna, G V.T | Xiao, R | Dna base repair | Methods development | Methyltransferase | Nesg | O6 methylguanine methyltransferase | PSI, Protein structure initiative | Solution nmr structure | Transferase
