2kcj
From Proteopedia
(Difference between revisions)
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==solution structure of FAPP1 PH domain== | ==solution structure of FAPP1 PH domain== | ||
- | <StructureSection load='2kcj' size='340' side='right' caption='[[2kcj]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2kcj' size='340' side='right'caption='[[2kcj]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2kcj]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kcj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KCJ FirstGlance]. <br> |
- | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLEKHA3, FAPP1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLEKHA3, FAPP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kcj OCA], [https://pdbe.org/2kcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kcj RCSB], [https://www.ebi.ac.uk/pdbsum/2kcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kcj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/PKHA3_HUMAN PKHA3_HUMAN]] Involved in Golgi to cell surface membrane traffic. Induces membrane tubulation. Binds preferentially to phosphatidylinositol 4-phosphate (PtdIns4P).<ref>PMID:15107860</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Coskun, U]] | [[Category: Coskun, U]] | ||
[[Category: James, J]] | [[Category: James, J]] |
Revision as of 08:16, 7 April 2021
solution structure of FAPP1 PH domain
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Categories: Human | Large Structures | Coskun, U | James, J | Lenoir, M | Overduin, M | Simons, K | Fapp1 | Lipid-binding | Membrane | Membrane protein | Ph domain