We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
2k6o
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Human LL-37 Structure== | ==Human LL-37 Structure== | ||
| - | <StructureSection load='2k6o' size='340' side='right' caption='[[2k6o]], [[NMR_Ensembles_of_Models | 4 NMR models]]' scene=''> | + | <StructureSection load='2k6o' size='340' side='right'caption='[[2k6o]], [[NMR_Ensembles_of_Models | 4 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k6o]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2k6o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. The June 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Dermcidin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_6 10.2210/rcsb_pdb/mom_2013_6]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K6O FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fbu|2fbu]], [[2fbs|2fbs]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fbu|2fbu]], [[2fbs|2fbs]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAMP, CAP18, FALL39, HSD26 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAMP, CAP18, FALL39, HSD26 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k6o OCA], [https://pdbe.org/2k6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k6o RCSB], [https://www.ebi.ac.uk/pdbsum/2k6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k6o ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CAMP_HUMAN CAMP_HUMAN]] Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.<ref>PMID:16637646</ref> <ref>PMID:18818205</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 35: | Line 35: | ||
[[Category: Dermcidin]] | [[Category: Dermcidin]] | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Wang, G]] | [[Category: Wang, G]] | ||
Revision as of 08:10, 7 April 2021
Human LL-37 Structure
| |||||||||||
Categories: Dermcidin | Human | Large Structures | RCSB PDB Molecule of the Month | Wang, G | Antibiotic | Antimicrobial | Antimicrobial peptide | Antimicrobial protein | Bacterial membrane targeting | Cleavage on pair of basic residue | Human cathelicidin | Human host defense peptide | Ll-37 | Pyrrolidone carboxylic acid | Secreted

