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2jy6

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==Solution structure of the complex of ubiquitin and ubiquilin 1 UBA domain==
==Solution structure of the complex of ubiquitin and ubiquilin 1 UBA domain==
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<StructureSection load='2jy6' size='340' side='right' caption='[[2jy6]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2jy6' size='340' side='right'caption='[[2jy6]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jy6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JY6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JY6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jy6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JY6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JY6 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jy5|2jy5]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jy5|2jy5]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBI1, RPL40A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), UBQLN1, DA41, PLIC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBI1, RPL40A ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), UBQLN1, DA41, PLIC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jy6 OCA], [http://pdbe.org/2jy6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jy6 RCSB], [http://www.ebi.ac.uk/pdbsum/2jy6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jy6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jy6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jy6 OCA], [https://pdbe.org/2jy6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jy6 RCSB], [https://www.ebi.ac.uk/pdbsum/2jy6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jy6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN]] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.
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[[https://www.uniprot.org/uniprot/UBQL1_HUMAN UBQL1_HUMAN]] Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Ubiquitin|Ubiquitin]]
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*[[3D structures of ubiquitin|3D structures of ubiquitin]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Fushman, D]]
[[Category: Fushman, D]]
[[Category: Raasi, S]]
[[Category: Raasi, S]]

Revision as of 08:01, 7 April 2021

Solution structure of the complex of ubiquitin and ubiquilin 1 UBA domain

PDB ID 2jy6

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