Interferon receptor
From Proteopedia
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== Disease == | == Disease == | ||
Mutations of interferon γ receptor confer susceptibility to infections caused by mycobacteria<ref>PMID:10192386</ref>. | Mutations of interferon γ receptor confer susceptibility to infections caused by mycobacteria<ref>PMID:10192386</ref>. | ||
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| + | ==3D structures of interferon receptor== | ||
| + | [[Interferon receptor 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
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**[[3se3]] – hINFAR2 ectodomain + hINFAR1 ectodomain + interferon-α 2 <br /> | **[[3se3]] – hINFAR2 ectodomain + hINFAR1 ectodomain + interferon-α 2 <br /> | ||
**[[3se4]] – hINFAR2 ectodomain + hINFAR1 ectodomain + interferon-ω 1 <br /> | **[[3se4]] – hINFAR2 ectodomain + hINFAR1 ectodomain + interferon-ω 1 <br /> | ||
| - | **[[3wcy]] – INFAR1 ectodomain + interferon-β - mouse <br /> | ||
**[[4po6]] – hINFDR1 residues 475-507 + TYK2 <br /> | **[[4po6]] – hINFDR1 residues 475-507 + TYK2 <br /> | ||
| + | **[[3wcy]] – INFAR1 ectodomain + interferon-β - mouse <br /> | ||
*Interferon γ receptor | *Interferon γ receptor | ||
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**[[1jrh]] – hINFGR1 N terminal (mutant) + antibody <br /> | **[[1jrh]] – hINFGR1 N terminal (mutant) + antibody <br /> | ||
**[[1fg9]], [[1fyh]] – hINFGR1 extracellular domain + interferon-γ <br /> | **[[1fg9]], [[1fyh]] – hINFGR1 extracellular domain + interferon-γ <br /> | ||
| - | **[[ | + | **[[6e3l]], [[6e3k]] – hINFGR1 extracellular domain (mutant) + hhINFGR2 + interferon-γ <br /> |
**[[5eh1]] – hINFGR2 extracellular domain <br /> | **[[5eh1]] – hINFGR2 extracellular domain <br /> | ||
| + | **[[4eq2]], [[4eq3]] – INFGR1 α chain - chicken <br /> | ||
*Interferon δ receptor | *Interferon δ receptor | ||
Revision as of 09:39, 2 September 2019
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3D structures of interferon receptor
Updated on 02-September-2019
References
- ↑ Uze G, Schreiber G, Piehler J, Pellegrini S. The receptor of the type I interferon family. Curr Top Microbiol Immunol. 2007;316:71-95. PMID:17969444
- ↑ Pestka S, Kotenko SV, Muthukumaran G, Izotova LS, Cook JR, Garotta G. The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor. Cytokine Growth Factor Rev. 1997 Sep;8(3):189-206. PMID:9462485
- ↑ Lefevre F, Guillomot M, D'Andrea S, Battegay S, La Bonnardiere C. Interferon-delta: the first member of a novel type I interferon family. Biochimie. 1998 Aug-Sep;80(8-9):779-88. PMID:9865499
- ↑ . PMID:16451483
- ↑ Santiago-Raber ML, Baccala R, Haraldsson KM, Choubey D, Stewart TA, Kono DH, Theofilopoulos AN. Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice. J Exp Med. 2003 Mar 17;197(6):777-88. PMID:12642605 doi:http://dx.doi.org/10.1084/jem.20021996
- ↑ Jouanguy E, Lamhamedi-Cherradi S, Lammas D, Dorman SE, Fondaneche MC, Dupuis S, Doffinger R, Altare F, Girdlestone J, Emile JF, Ducoulombier H, Edgar D, Clarke J, Oxelius VA, Brai M, Novelli V, Heyne K, Fischer A, Holland SM, Kumararatne DS, Schreiber RD, Casanova JL. A human IFNGR1 small deletion hotspot associated with dominant susceptibility to mycobacterial infection. Nat Genet. 1999 Apr;21(4):370-8. PMID:10192386 doi:http://dx.doi.org/10.1038/7701
