6ds0
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor== | |
| - | + | <StructureSection load='6ds0' size='340' side='right' caption='[[6ds0]], [[Resolution|resolution]] 3.19Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ds0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DS0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DS0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=H8M:(1S)-1-[(2-chloro-3,4-dimethoxyphenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1H-beta-carboline'>H8M</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ds0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ds0 OCA], [http://pdbe.org/6ds0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ds0 RCSB], [http://www.ebi.ac.uk/pdbsum/6ds0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ds0 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/5HT2B_HUMAN 5HT2B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Agegnehu, B]] | ||
[[Category: Che, T]] | [[Category: Che, T]] | ||
| - | [[Category: | + | [[Category: Jin, J]] |
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| - | + | ||
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[[Category: Lansu, K]] | [[Category: Lansu, K]] | ||
[[Category: Liu, J]] | [[Category: Liu, J]] | ||
| + | [[Category: McCorvy, J D]] | ||
| + | [[Category: Olsen, R H.J]] | ||
| + | [[Category: Roth, B L]] | ||
| + | [[Category: Tribo, A R]] | ||
| + | [[Category: Wacker, D]] | ||
[[Category: Wang, S]] | [[Category: Wang, S]] | ||
| - | [[Category: | + | [[Category: Gpcr]] |
| - | [[Category: | + | [[Category: Lisuride]] |
| - | [[Category: | + | [[Category: Membrane protein]] |
| + | [[Category: Setotonin receptor]] | ||
Revision as of 07:28, 29 August 2018
Structural Determinants of Activation and Biased Agonism at the 5-HT2B Receptor
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Categories: Agegnehu, B | Che, T | Jin, J | Lansu, K | Liu, J | McCorvy, J D | Olsen, R H.J | Roth, B L | Tribo, A R | Wacker, D | Wang, S | Gpcr | Lisuride | Membrane protein | Setotonin receptor
