2krm
From Proteopedia
(Difference between revisions)
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==RDC refined solution structure of the first SH3 domain of CD2AP== | ==RDC refined solution structure of the first SH3 domain of CD2AP== | ||
| - | <StructureSection load='2krm' size='340' side='right' caption='[[2krm]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | + | <StructureSection load='2krm' size='340' side='right'caption='[[2krm]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2krm]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2krm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRM FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j6k|2j6k]], [[2j6o|2j6o]], [[3krn|3krn]], [[3kro|3kro]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2j6k|2j6k]], [[2j6o|2j6o]], [[3krn|3krn]], [[3kro|3kro]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd2ap, Mets1 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd2ap, Mets1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krm OCA], [https://pdbe.org/2krm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krm RCSB], [https://www.ebi.ac.uk/pdbsum/2krm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krm ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/CD2AP_MOUSE CD2AP_MOUSE]] Required for cytokinesis (By similarity). Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.<ref>PMID:10514378</ref> |
==See Also== | ==See Also== | ||
| - | *[[CD2-associated protein|CD2-associated protein]] | + | *[[CD2-associated protein 3D structures|CD2-associated protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Azuaga, A I]] | [[Category: Azuaga, A I]] | ||
Revision as of 07:31, 14 April 2021
RDC refined solution structure of the first SH3 domain of CD2AP
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