This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2kx3
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==The solution structure of the mutant of UBL domain of UBLCP1, I5M== | ==The solution structure of the mutant of UBL domain of UBLCP1, I5M== | ||
| - | <StructureSection load='2kx3' size='340' side='right' caption='[[2kx3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2kx3' size='340' side='right'caption='[[2kx3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kx3]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kx3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KX3 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBLCP1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBLCP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kx3 OCA], [https://pdbe.org/2kx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kx3 RCSB], [https://www.ebi.ac.uk/pdbsum/2kx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kx3 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/UBCP1_HUMAN UBCP1_HUMAN]] Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.<ref>PMID:15883030</ref> <ref>PMID:21949367</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
| Line 15: | Line 15: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Phosphoprotein phosphatase]] | [[Category: Phosphoprotein phosphatase]] | ||
[[Category: Ko, S]] | [[Category: Ko, S]] | ||
Revision as of 07:33, 14 April 2021
The solution structure of the mutant of UBL domain of UBLCP1, I5M
| |||||||||||
Categories: Human | Large Structures | Phosphoprotein phosphatase | Ko, S | Lee, N | Ctd-phosphatase | Hydrolase | Mutant | Ubl domain | Ublcp1
