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2lcl
From Proteopedia
(Difference between revisions)
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==Solution Structure of RfaH carboxyterminal domain== | ==Solution Structure of RfaH carboxyterminal domain== | ||
| - | <StructureSection load='2lcl' size='340' side='right' caption='[[2lcl]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2lcl' size='340' side='right'caption='[[2lcl]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lcl]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lcl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eco57 Eco57]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LCL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LCL FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rfaH, hlyT, sfrB, Z5362, ECs4770 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rfaH, hlyT, sfrB, Z5362, ECs4770 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lcl OCA], [https://pdbe.org/2lcl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lcl RCSB], [https://www.ebi.ac.uk/pdbsum/2lcl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lcl ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/RFAH_ECO57 RFAH_ECO57]] Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Transcriptional activator|Transcriptional activator]] | + | *[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Eco57]] | [[Category: Eco57]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Burmann, B M]] | [[Category: Burmann, B M]] | ||
[[Category: Roesch, P]] | [[Category: Roesch, P]] | ||
Revision as of 10:08, 12 May 2021
Solution Structure of RfaH carboxyterminal domain
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