2lfe
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A== | ==Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A== | ||
| - | <StructureSection load='2lfe' size='340' side='right' caption='[[2lfe]], [[NMR_Ensembles_of_Models | 16 NMR models]]' scene=''> | + | <StructureSection load='2lfe' size='340' side='right'caption='[[2lfe]], [[NMR_Ensembles_of_Models | 16 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lfe]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lfe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LFE FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HECW2, KIAA1301, NEDL2 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HECW2, KIAA1301, NEDL2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lfe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfe OCA], [https://pdbe.org/2lfe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lfe RCSB], [https://www.ebi.ac.uk/pdbsum/2lfe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lfe ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HECW2_HUMAN HECW2_HUMAN]] E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. |
==See Also== | ==See Also== | ||
| - | *[[Ubiquitin protein ligase|Ubiquitin protein ligase]] | + | *[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C]] | [[Category: Arrowsmith, C]] | ||
[[Category: Chitayat, S]] | [[Category: Chitayat, S]] | ||
Revision as of 10:09, 12 May 2021
Solution NMR structure of N-terminal domain of human E3 ubiquitin-protein ligase HECW2, Northeast structural genomics consortium (NESG) target ht6306A
| |||||||||||
Categories: Human | Large Structures | Arrowsmith, C | Chitayat, S | Dhe-Paganon, S | Garcia, M | Houliston, S | Lemak, A | Montelione, G T | Structural genomic | Yee, A | Ligase | Nesg | Psi-biology | Sgc
