This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5zlh
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Mn-ProtoporphyrinIX-reconstituted P450BM3== | |
| + | <StructureSection load='5zlh' size='340' side='right' caption='[[5zlh]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5zlh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZLH FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNH:MANGANESE+PROTOPORPHYRIN+IX'>MNH</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5zis|5zis]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zlh OCA], [http://pdbe.org/5zlh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zlh RCSB], [http://www.ebi.ac.uk/pdbsum/5zlh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zlh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Haem substitution is an effective approach to tweak the function of haemoproteins. Herein, we report a facile haem substitution method for self-sufficient cytochrome P450BM3 (CYP102A1) from Bacillus megaterium utilising the transpeptidase Sortase A from Staphylococcus aureus. We successfully constructed Mn-substituted BM3 and investigated its catalytic activity. | ||
| - | + | Reconstitution of full-length P450BM3 with an artificial metal complex by utilising the transpeptidase Sortase A.,Omura K, Aiba Y, Onoda H, Stanfield JK, Ariyasu S, Sugimoto H, Shiro Y, Shoji O, Watanabe Y Chem Commun (Camb). 2018 Jul 12;54(57):7892-7895. doi: 10.1039/c8cc02760a. PMID:29845154<ref>PMID:29845154</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 5zlh" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Aiba, Y]] | ||
| + | [[Category: Omura, K]] | ||
[[Category: Onoda, H]] | [[Category: Onoda, H]] | ||
[[Category: Shoji, O]] | [[Category: Shoji, O]] | ||
[[Category: Sugimoto, H]] | [[Category: Sugimoto, H]] | ||
| - | [[Category: Aiba, Y]] | ||
| - | [[Category: Omura, K]] | ||
[[Category: Watanabe, Y]] | [[Category: Watanabe, Y]] | ||
| + | [[Category: Cytochrome p450]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 16:09, 15 August 2018
Crystal structure of Mn-ProtoporphyrinIX-reconstituted P450BM3
| |||||||||||
Categories: Aiba, Y | Omura, K | Onoda, H | Shoji, O | Sugimoto, H | Watanabe, Y | Cytochrome p450 | Oxidoreductase
