6dxr
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the Monoclinic-2 (Monocl-2) Crystal Form of Human Apolipoprotein C1== | |
| - | + | <StructureSection load='6dxr' size='340' side='right' caption='[[6dxr]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dxr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DXR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DXR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dxr OCA], [http://pdbe.org/6dxr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dxr RCSB], [http://www.ebi.ac.uk/pdbsum/6dxr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dxr ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/APOC1_HUMAN APOC1_HUMAN]] Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.<ref>PMID:17339654</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: McPherson, A]] | ||
| + | [[Category: Alpha helix]] | ||
| + | [[Category: Lipid]] | ||
| + | [[Category: Lipid binding protein]] | ||
| + | [[Category: Lipoprotein particle]] | ||
Revision as of 08:16, 26 December 2018
Structure of the Monoclinic-2 (Monocl-2) Crystal Form of Human Apolipoprotein C1
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