6e4l

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'''Unreleased structure'''
 
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The entry 6e4l is ON HOLD until Paper Publication
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==The structure of the N-terminal domain of human clathrin heavy chain 1 (nTD) in complex with ES9==
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<StructureSection load='6e4l' size='340' side='right'caption='[[6e4l]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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Authors: Dejonghe, W., Sharma, I., Denoo, B., Munck, S.D., Bulut, H., Mylle, E., Vasileva, M., Lu, Q., Savatin, D.V., Mishev, K., Nerinckx, W., Staes, A., Drozdzecki, A., Audenaert, D., Madder, A., Friml, J., Damme, D.V., Gevaert, K., Haucke, V., Savvides, S., Winne, J., Russinova, E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6e4l]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E4L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E4L FirstGlance]. <br>
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Description: The structure of the N-terminal domain of human clathrin heavy chain 1 (nTD) in complex with ES9
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HRS:5-bromo-N-(4-nitrophenyl)thiophene-2-sulfonamide'>HRS</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e4l OCA], [http://pdbe.org/6e4l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e4l RCSB], [http://www.ebi.ac.uk/pdbsum/6e4l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e4l ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/CLH1_HUMAN CLH1_HUMAN]] Translocation renal cell carcinoma;Inflammatory myofibroblastic tumor.
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== Function ==
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[[http://www.uniprot.org/uniprot/CLH1_HUMAN CLH1_HUMAN]] Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Audenaert, D]]
[[Category: Audenaert, D]]
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[[Category: Nerinckx, W]]
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[[Category: Bulut, H]]
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[[Category: Savatin, D.V]]
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[[Category: Damme, D V]]
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[[Category: Mylle, E]]
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[[Category: Dejonghe, W]]
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[[Category: Denoo, B]]
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[[Category: Drozdzecki, A]]
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[[Category: Friml, J]]
[[Category: Gevaert, K]]
[[Category: Gevaert, K]]
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[[Category: Bulut, H]]
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[[Category: Haucke, V]]
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[[Category: Staes, A]]
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[[Category: Lu, Q]]
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[[Category: Winne, J]]
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[[Category: Madder, A]]
[[Category: Madder, A]]
[[Category: Mishev, K]]
[[Category: Mishev, K]]
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[[Category: Munck, S D]]
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[[Category: Mylle, E]]
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[[Category: Nerinckx, W]]
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[[Category: Russinova, E]]
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[[Category: Savatin, D V]]
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[[Category: Savvides, S]]
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[[Category: Sharma, I]]
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[[Category: Staes, A]]
[[Category: Vasileva, M]]
[[Category: Vasileva, M]]
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[[Category: Damme, D.V]]
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[[Category: Winne, J]]
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[[Category: Sharma, I]]
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[[Category: Chemical inhibition]]
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[[Category: Drozdzecki, A]]
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[[Category: Endocytosis]]
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[[Category: Munck, S.D]]
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[[Category: Denoo, B]]
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[[Category: Savvides, S]]
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[[Category: Russinova, E]]
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[[Category: Dejonghe, W]]
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[[Category: Friml, J]]
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[[Category: Lu, Q]]
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[[Category: Haucke, V]]
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Revision as of 06:39, 24 April 2019

The structure of the N-terminal domain of human clathrin heavy chain 1 (nTD) in complex with ES9

PDB ID 6e4l

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