6h64
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the CRD-SAT== | |
| - | + | <StructureSection load='6h64' size='340' side='right'caption='[[6h64]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6h64]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H64 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LBT:ALPHA-LACTOSE'>LBT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h64 OCA], [http://pdbe.org/6h64 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h64 RCSB], [http://www.ebi.ac.uk/pdbsum/6h64 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h64 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN]] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Charron, C]] | [[Category: Charron, C]] | ||
| - | [[Category: | + | [[Category: Jouzeau, J Y]] |
[[Category: Kriznik, A]] | [[Category: Kriznik, A]] | ||
[[Category: Reboul, P]] | [[Category: Reboul, P]] | ||
| - | [[Category: | + | [[Category: Yelehe-Okouma, M]] |
| + | [[Category: Carbohydrate recognition domain]] | ||
| + | [[Category: Sugar binding protein]] | ||
Revision as of 16:28, 14 August 2019
Crystal structure of the CRD-SAT
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