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2mdk
From Proteopedia
(Difference between revisions)
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==NMR Solution Structure of MSP-P56S Domain/VAPB in DPC== | ==NMR Solution Structure of MSP-P56S Domain/VAPB in DPC== | ||
| - | <StructureSection load='2mdk' size='340' side='right' caption='[[2mdk]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> | + | <StructureSection load='2mdk' size='340' side='right'caption='[[2mdk]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2mdk]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2mdk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDK FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VAPB ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VAPB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdk OCA], [https://pdbe.org/2mdk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdk RCSB], [https://www.ebi.ac.uk/pdbsum/2mdk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdk ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN]] Adult-onset proximal spinal muscular atrophy, autosomal dominant;Amyotrophic lateral sclerosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN]] Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.<ref>PMID:16891305</ref> <ref>PMID:20940299</ref> <ref>PMID:22131369</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Vesicle-associated membrane protein|Vesicle-associated membrane protein]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Lim, L]] | [[Category: Lim, L]] | ||
[[Category: Qin, H]] | [[Category: Qin, H]] | ||
Revision as of 10:08, 26 May 2021
NMR Solution Structure of MSP-P56S Domain/VAPB in DPC
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Categories: Human | Large Structures | Lim, L | Qin, H | Song, J | Membrane protein | Msp-p56s domain | Vapb
