2lx7
From Proteopedia
(Difference between revisions)
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==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A== | ==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A== | ||
| - | <StructureSection load='2lx7' size='340' side='right' caption='[[2lx7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2lx7' size='340' side='right'caption='[[2lx7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LX7 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAS7, KIAA0394 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GAS7, KIAA0394 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lx7 OCA], [https://pdbe.org/2lx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2lx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lx7 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX. |
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] May play a role in promoting maturation and morphological differentiation of cerebellar neurons. |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Acton, T]] | [[Category: Acton, T]] | ||
[[Category: Dan, L]] | [[Category: Dan, L]] | ||
Revision as of 10:55, 19 May 2021
Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A
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