2mj7
From Proteopedia
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==Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C== | ==Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C== | ||
| - | <StructureSection load='2mj7' size='340' side='right' caption='[[2mj7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='2mj7' size='340' side='right'caption='[[2mj7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2mj7]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2mj7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MJ7 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AP4B1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AP4B1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mj7 OCA], [https://pdbe.org/2mj7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mj7 RCSB], [https://www.ebi.ac.uk/pdbsum/2mj7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mj7 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN]] Severe intellectual deficit and progressive spastic paraplegia. The disease is caused by mutations affecting the gene represented in this entry. |
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/AP4B1_HUMAN AP4B1_HUMAN]] Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. |
| + | |||
| + | ==See Also== | ||
| + | *[[Adaptin 3D structures|Adaptin 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Eletsky, A]] | [[Category: Eletsky, A]] | ||
[[Category: Everett, J K]] | [[Category: Everett, J K]] | ||
Revision as of 15:15, 2 June 2021
Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C
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