Nitroreductase

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Line 24: Line 24:
**[[1nec]], [[1kqd]] – EclNR – ''Enterobacter cloacae''<br />
**[[1nec]], [[1kqd]] – EclNR – ''Enterobacter cloacae''<br />
**[[1ywq]], [[2i7h]] – NR – ''Bacillus cereus''<br />
**[[1ywq]], [[2i7h]] – NR – ''Bacillus cereus''<br />
 +
**[[5hdj]] – NR – ''Bacillus megaterium''<br />
**[[2b67]] – NR – ''Streptococcus pneumonia''<br />
**[[2b67]] – NR – ''Streptococcus pneumonia''<br />
**[[3ek3]], [[3hoi]] – NR – ''Bacterioides fragilis''<br />
**[[3ek3]], [[3hoi]] – NR – ''Bacterioides fragilis''<br />
Line 49: Line 50:
**[[4bn9]] – LlNR + nicotinic acid<br />
**[[4bn9]] – LlNR + nicotinic acid<br />
**[[4bnb]] – LlNR + nitroquinoline<br />
**[[4bnb]] – LlNR + nitroquinoline<br />
 +
 +
*Nitrobenzoate nitroreductase
 +
 +
**[[4z85]] – NR – ''Psudomonas fluorescens''<br />
*Nitroreductase binary complex
*Nitroreductase binary complex
Line 59: Line 64:
**[[1oo6]], [[1oon]], [[1idt]] – EcNR + benzamide derivative<br />
**[[1oo6]], [[1oon]], [[1idt]] – EcNR + benzamide derivative<br />
**[[1yki]] – EcNR + antibiotic<br />
**[[1yki]] – EcNR + antibiotic<br />
-
**[[2wzw]] - MsNR + NADPH
+
**[[2wzw]] - MsNR + NADPH<br />
 +
**[[6czp]] – NR + FMN – ''Vibrio vulnificus''<br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:29, 15 August 2018

E. coli nitroreductase dimer containing FMN and nicotinic acid (PDB entry 1icr)

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3D structures of nitroreductase

Updated on 15-August-2018

References

  1. Lovering AL, Hyde EI, Searle PF, White SA. The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution. J Mol Biol. 2001 May 25;309(1):203-13. PMID:11491290 doi:10.1006/jmbi.2001.4653
  2. Williams EM, Little RF, Mowday AM, Rich MH, Chan-Hyams JV, Copp JN, Smaill JB, Patterson AV, Ackerley DF. Nitroreductase gene-directed enzyme prodrug therapy: insights and advances toward clinical utility. Biochem J. 2015 Oct 15;471(2):131-53. doi: 10.1042/BJ20150650. PMID:26431849 doi:http://dx.doi.org/10.1042/BJ20150650

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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