6e48

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'''Unreleased structure'''
 
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The entry 6e48 is ON HOLD until Paper Publication
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==Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid==
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<StructureSection load='6e48' size='340' side='right' caption='[[6e48]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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Authors: Nelson, C.A., Fremont, D.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6e48]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E48 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E48 FirstGlance]. <br>
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Description: Protruding Domain of Murine Norovirus in Complex with the CD300lf Receptor and Lithocholic Acid
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4OA:(3BETA,5BETA,14BETA,17ALPHA)-3-HYDROXYCHOLAN-24-OIC+ACID'>4OA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lq6|3lq6]]</td></tr>
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[[Category: Fremont, D.H]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e48 OCA], [http://pdbe.org/6e48 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e48 RCSB], [http://www.ebi.ac.uk/pdbsum/6e48 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e48 ProSAT]</span></td></tr>
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[[Category: Nelson, C.A]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CLM1_MOUSE CLM1_MOUSE]] Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.<ref>PMID:14662855</ref> <ref>PMID:17438331</ref> <ref>PMID:18097021</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Fremont, D H]]
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[[Category: Nelson, C A]]
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[[Category: Bile acid]]
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[[Category: Capsid protein]]
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[[Category: Clm-1]]
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[[Category: Clm1]]
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[[Category: Cmrf-35-like molecule-1]]
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[[Category: Dir2]]
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[[Category: Igsf13]]
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[[Category: Irem1]]
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[[Category: Lca]]
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[[Category: Lmir3]]
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[[Category: Myeloid receptor]]
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[[Category: Norovirus]]
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[[Category: Pigr3]]
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[[Category: Protruding domain]]
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[[Category: Viral protein]]

Revision as of 07:37, 12 September 2018

Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid

6e48, resolution 1.80Å

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