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6ecm
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of SNX15 PX domain in domain swapped conformation== | |
| - | + | <StructureSection load='6ecm' size='340' side='right' caption='[[6ecm]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ecm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ECM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ECM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ecm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ecm OCA], [http://pdbe.org/6ecm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ecm RCSB], [http://www.ebi.ac.uk/pdbsum/6ecm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ecm ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SNX15_HUMAN SNX15_HUMAN]] May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN.<ref>PMID:11085978</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Chandra, M]] | [[Category: Chandra, M]] | ||
| + | [[Category: Collins, B M]] | ||
| + | [[Category: Endosome]] | ||
| + | [[Category: Lipid binding protein]] | ||
| + | [[Category: Px domain]] | ||
| + | [[Category: Sorting nexin]] | ||
| + | [[Category: Trafficking]] | ||
Revision as of 06:09, 22 August 2018
Crystal Structure of SNX15 PX domain in domain swapped conformation
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