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2o2t
From Proteopedia
(Difference between revisions)
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==The crystal structure of the 1st PDZ domain of MPDZ== | ==The crystal structure of the 1st PDZ domain of MPDZ== | ||
| - | <StructureSection load='2o2t' size='340' side='right' caption='[[2o2t]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='2o2t' size='340' side='right'caption='[[2o2t]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2o2t]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2o2t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O2T FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MPDZ, MUPP1 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MPDZ, MUPP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o2t OCA], [https://pdbe.org/2o2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o2t RCSB], [https://www.ebi.ac.uk/pdbsum/2o2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o2t ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/MPDZ_HUMAN MPDZ_HUMAN]] Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.<ref>PMID:11150294</ref> <ref>PMID:15312654</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C]] | [[Category: Arrowsmith, C]] | ||
[[Category: Berridge, G]] | [[Category: Berridge, G]] | ||
Revision as of 15:59, 8 June 2021
The crystal structure of the 1st PDZ domain of MPDZ
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Categories: Human | Large Structures | Arrowsmith, C | Berridge, G | Doyle, D A | Edwards, A | Elkins, J | Gileadi, C | Gorrec, F | Johansson, C | Papagrigoriou, E | Phillips, C | Pike, A C.W | Structural genomic | Salah, E | Savitsky, P | Sundstrom, M | Umeano, C | Weigelt, J | Sgc | Structural protein
