2n5z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Mycobacterium tuberculosis: a dynamic view of the resuscitation promoting factor RpfC catalytic domain==
==Mycobacterium tuberculosis: a dynamic view of the resuscitation promoting factor RpfC catalytic domain==
-
<StructureSection load='2n5z' size='340' side='right' caption='[[2n5z]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2n5z' size='340' side='right'caption='[[2n5z]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2n5z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N5Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N5Z FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2n5z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N5Z FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTCY180.34, rpfC, Rv1884c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MTCY180.34, rpfC, Rv1884c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n5z OCA], [http://pdbe.org/2n5z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n5z RCSB], [http://www.ebi.ac.uk/pdbsum/2n5z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n5z ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n5z OCA], [https://pdbe.org/2n5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n5z RCSB], [https://www.ebi.ac.uk/pdbsum/2n5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n5z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RPFC_MYCTU RPFC_MYCTU]] Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity.<ref>PMID:12410821</ref> Stimulates growth of stationary phase M.bovis (a slow-growing Mycobacterium), reduces the lag phase of diluted fast-growers M.smegmatis and Micrococcus luteus. Sequential gene disruption indicates RpfB and RpfE are higher than RpfD and RpfC in functional hierarchy.<ref>PMID:12410821</ref>
+
[[https://www.uniprot.org/uniprot/RPFC_MYCTU RPFC_MYCTU]] Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity.<ref>PMID:12410821</ref> Stimulates growth of stationary phase M.bovis (a slow-growing Mycobacterium), reduces the lag phase of diluted fast-growers M.smegmatis and Micrococcus luteus. Sequential gene disruption indicates RpfB and RpfE are higher than RpfD and RpfC in functional hierarchy.<ref>PMID:12410821</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Myctu]]
[[Category: Isernia, C]]
[[Category: Isernia, C]]

Revision as of 15:40, 8 June 2021

Mycobacterium tuberculosis: a dynamic view of the resuscitation promoting factor RpfC catalytic domain

PDB ID 2n5z

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools