Peptidyl-tRNA hydrolase

(Difference between revisions)

Revision as of 12:19, 31 July 2019

Structure of peptidyl-tRNA hydrolase complex with tRNA CCA acceptor domain (PDB entry 3vjr)

Drag the structure with the mouse to rotate

Updated on 31-July-2019

↑ Das G, Varshney U. Peptidyl-tRNA hydrolase and its critical role in protein biosynthesis. Microbiology. 2006 Aug;152(Pt 8):2191-5. PMID:16849786 doi:http://dx.doi.org/10.1099/mic.0.29024-0
↑ Ito K, Murakami R, Mochizuki M, Qi H, Shimizu Y, Miura KI, Ueda T, Uchiumi T. Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase. Nucleic Acids Res. 2012 Aug 25. PMID:22923517 doi:10.1093/nar/gks790

@@ Line 4: / Line 4: @@
 == Structural highlights ==
-PTH dimer interacts with tRNA at the latter's <scene name='55/551222/Cv/2'>CCA - the 3' end of the molecule which binds the amino acid</scene>; the <scene name='55/551222/Cv/3'>acceptor site which pass-pairs tRNA N-terminal nucleotides to the C-terminal nucleotides</scene> and the TΨC site (Ψ is pseudouridine) which is the <scene name='55/551222/Cv/4'>tRNA ribosome recognition site</scene><ref>PMID:22923517</ref>.
+PTH dimer interacts with tRNA at the latter's <scene name='55/551222/Cv/5'>CCA - the 3' end of the molecule which binds the amino acid</scene>; the <scene name='55/551222/Cv/6'>acceptor site which pass-pairs tRNA N-terminal nucleotides to the C-terminal nucleotides</scene> and the TΨC site (Ψ is pseudouridine) which is the <scene name='55/551222/Cv/7'>tRNA ribosome recognition site</scene><ref>PMID:22923517</ref>.
 </StructureSection>