2p8h

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[[Image:2p8h.jpg|left|200px]]
[[Image:2p8h.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 2p8h |SIZE=350|CAPTION= <scene name='initialview01'>2p8h</scene>, resolution 1.80&Aring;
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The line below this paragraph, containing "STRUCTURE_2p8h", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=MY9:N-{(1S,2S)-1-BENZYL-2-HYDROXY-2-[(4S)-1,2,2-TRIMETHYL-5-OXOIMIDAZOLIDIN-4-YL]ETHYL}-N&#39;-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-5-[METHYL(METHYLSULFONYL)AMINO]ISOPHTHALAMIDE'>MY9</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= BACE1, BACE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_2p8h| PDB=2p8h | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p8h OCA], [http://www.ebi.ac.uk/pdbsum/2p8h PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p8h RCSB]</span>
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}}
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'''Crystal structure of human beta secretase complexed with inhibitor'''
'''Crystal structure of human beta secretase complexed with inhibitor'''
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[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Munshi, S.]]
[[Category: Munshi, S.]]
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[[Category: aspartyl protease]]
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[[Category: Aspartyl protease]]
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[[Category: bace]]
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[[Category: Bace]]
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[[Category: hydrolase]]
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[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 12:36:14 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:32:17 2008''
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Revision as of 09:36, 4 May 2008

Image:2p8h.jpg

Template:STRUCTURE 2p8h

Crystal structure of human beta secretase complexed with inhibitor


About this Structure

2P8H is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1., Barrow JC, Rittle KE, Ngo PL, Selnick HG, Graham SL, Pitzenberger SM, McGaughey GB, Colussi D, Lai MT, Huang Q, Tugusheva K, Espeseth AS, Simon AJ, Munshi SK, Vacca JP, ChemMedChem. 2007 Jul 9;2(7):995-999. PMID:17458843 Page seeded by OCA on Sun May 4 12:36:14 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

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