Poly(A) RNA polymerase
From Proteopedia
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== Function == | == Function == | ||
| - | '''Poly(A) RNA polymerase protein Cid1''' (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis<ref>PMID:17072891</ref>. Cid1 is found in fission yeast. Cid1 exists in 3 forms: '''apo I''' consists of 4 subunits; '''apo II''' consists of 2 subunits; '''UTP-bound''' form consists of 4 subunits. | + | '''Poly(A) RNA polymerase protein Cid1''' (Caffeine-Induced Death protein 1) is involved in cell cycle arrest where it inhibits unscheduled mitosis<ref>PMID:17072891</ref>. Cid1 is found in fission yeast. Cid1 exists in 3 forms: '''apo I''' consists of 4 subunits; '''apo II''' consists of 2 subunits; '''UTP-bound''' form consists of 4 subunits. <br /> |
| + | '''Poly(A) RNA polymerase Gld2''' is responsible for poly(A) tail lengthening. Gld2 activity in the brain is required for long-term memory<ref>PMID:15987816</ref>. | ||
== Structural highlights == | == Structural highlights == | ||
Revision as of 08:04, 23 August 2018
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3D Structures of poly(A) RNA polymerase protein Cid1
Updated on 23-August-2018
References
- ↑ Stevenson AL, Norbury CJ. The Cid1 family of non-canonical poly(A) polymerases. Yeast. 2006 Oct 15;23(13):991-1000. PMID:17072891 doi:http://dx.doi.org/10.1002/yea.1408
- ↑ Kachouri R, Stribinskis V, Zhu Y, Ramos KS, Westhof E, Li Y. A surprisingly large RNase P RNA in Candida glabrata. RNA. 2005 Jul;11(7):1064-72. doi: 10.1261/rna.2130705. PMID:15987816 doi:http://dx.doi.org/10.1261/rna.2130705
- ↑ Yates LA, Fleurdepine S, Rissland OS, De Colibus L, Harlos K, Norbury CJ, Gilbert RJ. Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat Struct Mol Biol. 2012 Jul 1. doi: 10.1038/nsmb.2329. PMID:22751018 doi:10.1038/nsmb.2329
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