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Profilin

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PFN from birch, peanut and other plants is a major allergen<ref>PMID:25123397</ref>.
PFN from birch, peanut and other plants is a major allergen<ref>PMID:25123397</ref>.
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== 3D Structures of profilin ==
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[[Profilin 3D Structures]]
</StructureSection>
</StructureSection>
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**[[1pne]] – bPFN – bovine <br />
**[[1pne]] – bPFN – bovine <br />
**[[1cqa]] – biPFN - birch <br />
**[[1cqa]] – biPFN - birch <br />
-
**[[3nul]], [[1a0k]] – PFN – ''Arabidopsis thaliana'' <br />
+
**[[3nul]], [[1a0k]] – AtPFN – ''Arabidopsis thaliana'' <br />
 +
**[[4esp]] – PFN – peanut <br />
 +
**[[5fef]] - PFN - maize<br />
 +
**[[5em0]] - PFN - mugwort<br />
 +
**[[5em1]] - rPFN - ragweed<br />
 +
**[[6b6j]] – PFN – mugwort<br />
 +
**[[6mbx]] – PFN – muskmelon<br />
**[[1ypr]], [[1k0k]] – PFN - yeast <br />
**[[1ypr]], [[1k0k]] – PFN - yeast <br />
**[[3d9y]], [[3dav]] – PFN – fission yeast <br />
**[[3d9y]], [[3dav]] – PFN – fission yeast <br />
**[[1g5u]] – PFN – ''Hevea brasiliensis'' <br />
**[[1g5u]] – PFN – ''Hevea brasiliensis'' <br />
**[[2jkf]], [[4d60]] – PfPFN – ''Plasmodium falciparum'' <br />
**[[2jkf]], [[4d60]] – PfPFN – ''Plasmodium falciparum'' <br />
-
**[[4esp]] – PFN – peanut <br />
 
**[[4qwo]] – PFN – monkeypox virus <br />
**[[4qwo]] – PFN – monkeypox virus <br />
**[[2prf]] – AcPFN – ''Acanthamoeba castellanii'' - NMR<br />
**[[2prf]] – AcPFN – ''Acanthamoeba castellanii'' - NMR<br />
**[[1prq]] – AcPFN <br />
**[[1prq]] – AcPFN <br />
**[[3nec]] – PFN – ''Toxoplasma gondii''<br />
**[[3nec]] – PFN – ''Toxoplasma gondii''<br />
-
**[[5fef]] - PFN - maize<br />
 
-
**[[5em0]] - PFN - mugwort<br />
 
-
**[[5em1]] - rPFN - ragweed<br />
 
*Profilin I complex
*Profilin I complex
 +
**[[1awi]], [[1cf0]], [[1cjf]] – hPFN + poly-Pro peptide <br />
 +
**[[2pav]], [[2pbd]], [[3chw]] – hPFN + α-actin + VASP poly-Pro peptide + ATP <br />
**[[2btf]], [[3u4l]], [[3ub5]] – bPFN + β-actin <br />
**[[2btf]], [[3u4l]], [[3ub5]] – bPFN + β-actin <br />
**[[1hlu]] – bPFN + β-actin + ATP <br />
**[[1hlu]] – bPFN + β-actin + ATP <br />
**[[2jkg]] – PfPFN + poly-Pro peptide <br />
**[[2jkg]] – PfPFN + poly-Pro peptide <br />
**[[5ev0]], [[5eve]] - rPFN + poly-Pro peptide<br />
**[[5ev0]], [[5eve]] - rPFN + poly-Pro peptide<br />
-
**[[1awi]], [[1cf0]], [[1cjf]] – hPFN + poly-Pro peptide <br />
 
-
**[[2pav]], [[2pbd]], [[3chw]] – hPFN + α-actin + VASP poly-Pro peptide + ATP <br />
 
*Profilin II
*Profilin II
-
**[[1acf]], [[2acg]], [[1f2k]] – AcPFN <br />
 
**[[1d1j]] – hPFN <br />
**[[1d1j]] – hPFN <br />
 +
**[[1acf]], [[2acg]], [[1f2k]] – AcPFN <br />
**[[2vk3]] – PFN - rat <br />
**[[2vk3]] – PFN - rat <br />
-
**[[5fds]], [[5feg]] - PFN - rubber tree<br />
 
**[[2v8c]] – mPFN + VASP poly-Pro peptide - mouse <br />
**[[2v8c]] – mPFN + VASP poly-Pro peptide - mouse <br />
**[[2v8f]] – mPFN + MDIA1 poly-Pro peptide <br />
**[[2v8f]] – mPFN + MDIA1 poly-Pro peptide <br />
 +
**[[5fds]], [[5feg]] - PFN - rubber tree<br />
**[[5nzb]], [[5nzc]] – biPFN <br />
**[[5nzb]], [[5nzc]] – biPFN <br />
 +
**[[6iqi]] – AtPFN <br />
 +
**[[6iqj]] – AtPFN + formin1 <br />
 +
**[[1acf]], [[2acg]], [[1f2k]] – AcPFN <br />
 +
 +
*Profilin III
 +
 +
**[[6iqf]] – AtPFN <br />
 +
 +
*Profilin V
 +
 +
**[[6iqk]] – AtPFN + ATPRF3 <br />
 +
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:42, 27 November 2019

Human profilin I (green) complex with α-actin (grey), VASP protein poly-Pro peptide (olive), ATP and Ca+2 ion (PDB code 2pbd)

Drag the structure with the mouse to rotate

3D Structures of profilin

Updated on 27-November-2019

References

  1. ↑ Nejedla M, Sara S, Sulimenko V, de Almeida FN, Blom H, Draber P, Aspenstrom P, Karlsson R. Profilin connects Actin Assembly with Microtubule dynamics. Mol Biol Cell. 2016 Jun 15. pii: mbc.E15-11-0799. PMID:27307590 doi:http://dx.doi.org/10.1091/mbc.E15-11-0799
  2. ↑ Alvarado MI, Jimeno L, De La Torre F, Boissy P, Rivas B, Lazaro MJ, Barber D. Profilin as a severe food allergen in allergic patients overexposed to grass pollen. Allergy. 2014 Dec;69(12):1610-6. doi: 10.1111/all.12509. Epub 2014 Oct 3. PMID:25123397 doi:http://dx.doi.org/10.1111/all.12509

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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