2pc6

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[[Image:2pc6.gif|left|200px]]
[[Image:2pc6.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2pc6 |SIZE=350|CAPTION= <scene name='initialview01'>2pc6</scene>, resolution 2.50&Aring;
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The line below this paragraph, containing "STRUCTURE_2pc6", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetolactate_synthase Acetolactate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.6 2.2.1.6] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= ilvH, NE1324 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=228410 Nitrosomonas europaea ATCC 19718])
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-->
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK11895 ilvH], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=CHL00100 ilvH], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04878 ACT_AHAS]</span>
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{{STRUCTURE_2pc6| PDB=2pc6 | SCENE= }}
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|RELATEDENTRY=[[2fgd|2FGD]], [[2fgc|2FGC]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pc6 OCA], [http://www.ebi.ac.uk/pdbsum/2pc6 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pc6 RCSB]</span>
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}}
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'''Crystal structure of putative acetolactate synthase- small subunit from Nitrosomonas europaea'''
'''Crystal structure of putative acetolactate synthase- small subunit from Nitrosomonas europaea'''
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==About this Structure==
==About this Structure==
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2PC6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea_atcc_19718 Nitrosomonas europaea atcc 19718]. This structure supersedes the now removed PDB entry 2FGD. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PC6 OCA].
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2PC6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea_atcc_19718 Nitrosomonas europaea atcc 19718]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fgd 2fgd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PC6 OCA].
==Reference==
==Reference==
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[[Category: Zheng, H.]]
[[Category: Zheng, H.]]
[[Category: Zimmerman, M D.]]
[[Category: Zimmerman, M D.]]
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[[Category: acetolactate synthase]]
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[[Category: Acetolactate synthase]]
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[[Category: lyase]]
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[[Category: Lyase]]
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[[Category: mcsg]]
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[[Category: Mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: Midwest center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: psi]]
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[[Category: Psi]]
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[[Category: regulatory subunit]]
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[[Category: Regulatory subunit]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 12:49:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:34:06 2008''
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Revision as of 09:49, 4 May 2008

Image:2pc6.gif

Template:STRUCTURE 2pc6

Crystal structure of putative acetolactate synthase- small subunit from Nitrosomonas europaea


Overview

Crystal structures of two orthologs of the regulatory subunit of acetohydroxyacid synthase III (AHAS, EC 2.2.1.6) from Thermotoga maritima (TM0549) and Nitrosomonas europea (NE1324) were determined by single-wavelength anomalous diffraction methods with the use of selenomethionine derivatives at 2.3 A and 2.5 A, respectively. TM0549 and NE1324 share the same fold, and in both proteins the polypeptide chain contains two separate domains of a similar size. Each protein contains a C-terminal domain with ferredoxin-type fold and an N-terminal ACT domain, of which the latter is characteristic for several proteins involved in amino acid metabolism. The ferredoxin domain is stabilized by a calcium ion in the crystal structure of NE1324 and by a Mg(H2O)(6)2+ ion in TM0549. Both TM0549 and NE1324 form dimeric assemblies in the crystal lattice.

About this Structure

2PC6 is a Single protein structure of sequence from Nitrosomonas europaea atcc 19718. This structure supersedes the now removed PDB entry 2fgd. Full crystallographic information is available from OCA.

Reference

Crystal structures of TM0549 and NE1324--two orthologs of E. coli AHAS isozyme III small regulatory subunit., Petkowski JJ, Chruszcz M, Zimmerman MD, Zheng H, Skarina T, Onopriyenko O, Cymborowski MT, Koclega KD, Savchenko A, Edwards A, Minor W, Protein Sci. 2007 Jul;16(7):1360-7. PMID:17586771 Page seeded by OCA on Sun May 4 12:49:25 2008

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