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2pth

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==PEPTIDYL-TRNA HYDROLASE FROM ESCHERICHIA COLI==
==PEPTIDYL-TRNA HYDROLASE FROM ESCHERICHIA COLI==
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<StructureSection load='2pth' size='340' side='right' caption='[[2pth]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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<StructureSection load='2pth' size='340' side='right'caption='[[2pth]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2pth]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PTH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2pth]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PTH FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aminoacyl-tRNA_hydrolase Aminoacyl-tRNA hydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.29 3.1.1.29] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pth OCA], [http://pdbe.org/2pth PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pth RCSB], [http://www.ebi.ac.uk/pdbsum/2pth PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pth ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pth OCA], [https://pdbe.org/2pth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pth RCSB], [https://www.ebi.ac.uk/pdbsum/2pth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pth ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PTH_ECOLI PTH_ECOLI]] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death.
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[[https://www.uniprot.org/uniprot/PTH_ECOLI PTH_ECOLI]] The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Involved in lambda inhibition of host protein synthesis. PTH activity may, directly or indirectly, be the target for lambda bar RNA leading to rap cell death.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Aminoacyl-tRNA hydrolase]]
[[Category: Aminoacyl-tRNA hydrolase]]
[[Category: Ecoli]]
[[Category: Ecoli]]
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[[Category: Large Structures]]
[[Category: Blanquet, S]]
[[Category: Blanquet, S]]
[[Category: Fromant, M]]
[[Category: Fromant, M]]

Revision as of 15:32, 17 June 2021

PEPTIDYL-TRNA HYDROLASE FROM ESCHERICHIA COLI

PDB ID 2pth

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