Retinoblastoma-binding protein

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== Structural highlights ==
== Structural highlights ==
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<scene name='48/485630/Cv/4'>RBBP7 interacts with histone H4 in a pocket between its N-terminal α helix</scene> and its negatively charged <scene name='48/485630/Cv/5'>PP loop which contains 2 consecutive Pro residues</scene><ref>PMID:18571423</ref>.<br />.
+
<scene name='48/485630/Cv/6'>RBBP7 interacts with histone H4 in a pocket between its N-terminal α helix</scene> and its negatively charged <scene name='48/485630/Cv/7'>PP loop which contains 2 consecutive Pro residues</scene><ref>PMID:18571423</ref>.<br />.
</StructureSection>
</StructureSection>
==3D structures of retinoblastoma-binding protein==
==3D structures of retinoblastoma-binding protein==

Revision as of 12:49, 25 August 2019

Human retinoblastoma-binding protein 7 (green) complex with histone H4 helix (magenta) and As ion (purple) 3cfs

Drag the structure with the mouse to rotate

3D structures of retinoblastoma-binding protein

Updated on 25-August-2019

References

  1. ↑ Woitach JT, Zhang M, Niu CH, Thorgeirsson SS. A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability. Nat Genet. 1998 Aug;19(4):371-4. PMID:9697699 doi:http://dx.doi.org/10.1038/1258
  2. ↑ Fattaey AR, Helin K, Dembski MS, Dyson N, Harlow E, Vuocolo GA, Hanobik MG, Haskell KM, Oliff A, Defeo-Jones D, et al.. Characterization of the retinoblastoma binding proteins RBP1 and RBP2. Oncogene. 1993 Nov;8(11):3149-56. PMID:8414517
  3. ↑ Motadi LR, Bhoola KD, Dlamini Z. Expression and function of retinoblastoma binding protein 6 (RBBP6) in human lung cancer. Immunobiology. 2011 Oct;216(10):1065-73. doi: 10.1016/j.imbio.2011.05.004. Epub, 2011 May 17. PMID:21676486 doi:http://dx.doi.org/10.1016/j.imbio.2011.05.004
  4. ↑ Yang J, Kiefer S, Rauchman M. Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes. Genomics. 2002 Oct;80(4):407-15. PMID:12376095
  5. ↑ Vorobiev SM, Huang YJ, Seetharaman J, Xiao R, Acton TB, Montelione GT, Tong L. Human retinoblastoma binding protein 9, a serine hydrolase implicated in pancreatic cancers. Protein Pept Lett. 2012 Feb;19(2):194-7. PMID:21933118
  6. ↑ Murzina NV, Pei XY, Zhang W, Sparkes M, Vicente-Garcia J, Pratap JV, McLaughlin SH, Ben-Shahar TR, Verreault A, Luisi BF, Laue ED. Structural basis for the recognition of histone H4 by the histone-chaperone RbAp46. Structure. 2008 Jul;16(7):1077-85. Epub 2008 Jun 19. PMID:18571423 doi:http://dx.doi.org/10.1016/j.str.2008.05.006

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