6e3i

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'''Unreleased structure'''
 
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The entry 6e3i is ON HOLD until Paper Publication
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==Human Bfl-1 in complex with the Bfl-1-specific designed peptide srt.F4==
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<StructureSection load='6e3i' size='340' side='right' caption='[[6e3i]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
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Authors: Jenson, J.M., Keating, A.E.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6e3i]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E3I FirstGlance]. <br>
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Description: Human Bfl-1 in complex with the Bfl-1-specific designed peptide srt.F4
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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[[Category: Jenson, J.M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e3i OCA], [http://pdbe.org/6e3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e3i RCSB], [http://www.ebi.ac.uk/pdbsum/6e3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e3i ProSAT]</span></td></tr>
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[[Category: Keating, A.E]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/B2LA1_HUMAN B2LA1_HUMAN]] Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity).
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__TOC__
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</StructureSection>
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[[Category: Jenson, J M]]
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[[Category: Keating, A E]]
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[[Category: Anti-apoptotic bcl-2]]
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[[Category: Apoptosis]]
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[[Category: Design]]
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[[Category: Inhibitor]]

Revision as of 08:00, 17 October 2018

Human Bfl-1 in complex with the Bfl-1-specific designed peptide srt.F4

6e3i, resolution 1.48Å

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