2qhs

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==Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B==
==Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B==
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<StructureSection load='2qhs' size='340' side='right' caption='[[2qhs]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='2qhs' size='340' side='right'caption='[[2qhs]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qhs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QHS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qhs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QHS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCA:OCTANOIC+ACID+(CAPRYLIC+ACID)'>OCA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OCA:OCTANOIC+ACID+(CAPRYLIC+ACID)'>OCA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qht|2qht]], [[2qhu|2qhu]], [[2qhv|2qhv]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2qht|2qht]], [[2qhu|2qhu]], [[2qhv|2qhv]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTC 1746 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTC 1746 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qhs OCA], [http://pdbe.org/2qhs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qhs RCSB], [http://www.ebi.ac.uk/pdbsum/2qhs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qhs ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qhs OCA], [https://pdbe.org/2qhs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qhs RCSB], [https://www.ebi.ac.uk/pdbsum/2qhs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qhs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LIPB_THET8 LIPB_THET8]] Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
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[[https://www.uniprot.org/uniprot/LIPB_THET8 LIPB_THET8]] Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Thet8]]
[[Category: Thet8]]
[[Category: Kim, D J]]
[[Category: Kim, D J]]

Revision as of 08:20, 25 June 2021

Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B

PDB ID 2qhs

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