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2rgi
From Proteopedia
(Difference between revisions)
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==Crystal structure of Ca2+-free S100A2 at 1.6 A resolution== | ==Crystal structure of Ca2+-free S100A2 at 1.6 A resolution== | ||
| - | <StructureSection load='2rgi' size='340' side='right' caption='[[2rgi]], [[Resolution|resolution]] 1.60Å' scene=''> | + | <StructureSection load='2rgi' size='340' side='right'caption='[[2rgi]], [[Resolution|resolution]] 1.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2rgi]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2rgi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RGI FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">S100A2, S100L ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">S100A2, S100L ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rgi OCA], [https://pdbe.org/2rgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rgi RCSB], [https://www.ebi.ac.uk/pdbsum/2rgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rgi ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/S10A2_HUMAN S10A2_HUMAN]] May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.<ref>PMID:1372446</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[S100 protein|S100 protein]] | *[[S100 protein|S100 protein]] | ||
| + | *[[S100 proteins 3D structures|S100 proteins 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Diez, J]] | [[Category: Diez, J]] | ||
[[Category: Fritz, G]] | [[Category: Fritz, G]] | ||
Revision as of 04:24, 2 July 2021
Crystal structure of Ca2+-free S100A2 at 1.6 A resolution
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