Rho GTPase
From Proteopedia
(Difference between revisions)
| Line 36: | Line 36: | ||
**[[3kz1]] – hRhoA + guanine nucleotide exchange factor 11 + GSP<br /> | **[[3kz1]] – hRhoA + guanine nucleotide exchange factor 11 + GSP<br /> | ||
**[[1x86]] – hRhoA + guanine nucleotide exchange factor 12<br /> | **[[1x86]] – hRhoA + guanine nucleotide exchange factor 12<br /> | ||
| + | **[[6bcb]] – hRhoA + guanine nucleotide exchange factor 18<br /> | ||
| + | **[[6bc0]] – hRhoA + guanine nucleotide exchange factor 28 + GTP analog<br /> | ||
*RhoA complex with Rho GTPase-activating protein | *RhoA complex with Rho GTPase-activating protein | ||
| Line 55: | Line 57: | ||
**[[4xoi]] – hRhoA (mutant) + actin-binding protein anillin + GTP <br /> | **[[4xoi]] – hRhoA (mutant) + actin-binding protein anillin + GTP <br /> | ||
**[[4f38]] – mRhoA + Rho GDP-dissociation inhibitor 1 + GPPNP <br /> | **[[4f38]] – mRhoA + Rho GDP-dissociation inhibitor 1 + GPPNP <br /> | ||
| - | **[[4d0n]] – hRhoA + A-kinase anchor protein 13 + GDP<br /> | + | **[[4d0n]], [[6bca]] – hRhoA + A-kinase anchor protein 13 + GDP<br /> |
**[[3lw8]], [[3lwn]], [[3lxr]] – hRhoA + IpgB2 + GDP<br /> | **[[3lw8]], [[3lwn]], [[3lxr]] – hRhoA + IpgB2 + GDP<br /> | ||
**[[1s1c]] – hRhoA + ROCKI + GNP<br /> | **[[1s1c]] – hRhoA + ROCKI + GNP<br /> | ||
| Line 63: | Line 65: | ||
**[[5c2k]] – hRhoA/Rac GTPase-activating protein 1 + GDP <br /> | **[[5c2k]] – hRhoA/Rac GTPase-activating protein 1 + GDP <br /> | ||
**[[5jcp]] – hRhoA/ARAP3 + GDP <br /> | **[[5jcp]] – hRhoA/ARAP3 + GDP <br /> | ||
| + | **[[5zhx]] – hRhoA (mutant) + RAP1 <br /> | ||
*RhoB | *RhoB | ||
Revision as of 09:40, 6 September 2018
| |||||||||||
3D structures of Rho GTPase
Updated on 06-September-2018
References
- ↑ Sepp KJ, Auld VJ. RhoA and Rac1 GTPases mediate the dynamic rearrangement of actin in peripheral glia. Development. 2003 May;130(9):1825-35. PMID:12642488
- ↑ Fransson A, Ruusala A, Aspenstrom P. Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. J Biol Chem. 2003 Feb 21;278(8):6495-502. Epub 2002 Dec 12. PMID:12482879 doi:http://dx.doi.org/10.1074/jbc.M208609200
- ↑ Zhou J, Hayakawa Y, Wang TC, Bass AJ. RhoA mutations identified in diffuse gastric cancer. Cancer Cell. 2014 Jul 14;26(1):9-11. doi: 10.1016/j.ccr.2014.06.022. PMID:25026207 doi:http://dx.doi.org/10.1016/j.ccr.2014.06.022
- ↑ Jin L, Burnett AL. RhoA/Rho-kinase in erectile tissue: mechanisms of disease and therapeutic insights. Clin Sci (Lond). 2006 Feb;110(2):153-65. PMID:16411892 doi:http://dx.doi.org/10.1042/CS20050255
- ↑ Rittinger K, Walker PA, Eccleston JF, Smerdon SJ, Gamblin SJ. Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature. 1997 Oct 16;389(6652):758-62. PMID:9338791 doi:10.1038/39651
