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Transcriptional activator

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Line 49: Line 49:
**[[2c99]] – EcTA AAA domain + AMPPNP<br />
**[[2c99]] – EcTA AAA domain + AMPPNP<br />
**[[2vii]] – EcTA AAA domain + AMP + Mg<br />
**[[2vii]] – EcTA AAA domain + AMP + Mg<br />
 +
**[[5nss]] – EcTA AAA domain + RNAP subunits αββ'ω + DNA - Cryo EM<br />
*TenA transcriptional activator
*TenA transcriptional activator
Line 62: Line 63:
**[[2uv0]] – PaTA LBD – ''Pseudomonas aeruginosa''<br />
**[[2uv0]] – PaTA LBD – ''Pseudomonas aeruginosa''<br />
**[[3ix3]] – PaTA LBD + oxo-dodecanoyl-homoserine lactone<br />
**[[3ix3]] – PaTA LBD + oxo-dodecanoyl-homoserine lactone<br />
-
**[[3ix4]], [[3ix8]], [[3jpu]] – PaTA LBD + benzoate derivative<br />
+
**[[3ix4]], [[3ix8]], [[3jpu]], [[6d6a]], [[6d6b]], [[6d6c]], [[6d6d]], [[6d6l]], [[6d6m]], [[6d6n]], [[6d6o]], [[6d6p]] – PaTA LBD + benzoate derivative<br />
**[[4ng2]] – PaTA LBD + protein<br />
**[[4ng2]] – PaTA LBD + protein<br />
-
*CadC transcriptional activator
+
*CadC transcriptional activator; domains - DBD 1-107; periplasmic 188-512
**[[3ly7]], [[3lya]] – EcTA periplasmic domain <br />
**[[3ly7]], [[3lya]] – EcTA periplasmic domain <br />
**[[3ly8]], [[3ly9]] – EcTA periplasmic domain (mutant)<br />
**[[3ly8]], [[3ly9]] – EcTA periplasmic domain (mutant)<br />
 +
**[[5ju7]] – EcTA DBD domain <br />
*CynR transcriptional activator
*CynR transcriptional activator
Line 82: Line 84:
*Brg1 transcriptional activator
*Brg1 transcriptional activator
-
**[[3uvd]] – TA bromodomain + pyrrolidone derivative - human<br />
+
**[[5ea1]] – hTA bromodomain - human<br />
 +
**[[3uvd]] – hTA bromodomain + pyrrolidone derivative <br />
 +
**[[5dkd]] – hTA bromodomain + pyridine derivative <br />
*VP30 transcriptional activator
*VP30 transcriptional activator
Line 91: Line 95:
*TraR transcriptional activator
*TraR transcriptional activator
 +
**[[1v4r]] – AtTA N-terminal - ''Streptomyces'' - NMR <br />
**[[1l3l]] – AtTA + pheromone + DNA – ''Agrobacterium tumefaciens'' <br />
**[[1l3l]] – AtTA + pheromone + DNA – ''Agrobacterium tumefaciens'' <br />
**[[1h0m]] – AtTA + auto-inducer + DNA <br />
**[[1h0m]] – AtTA + auto-inducer + DNA <br />
 +
**[[5w1s]] – EcTA + RNAP subunits αββ'ω + PROD + DNA <br />
*Flagelar transcriptional activator
*Flagelar transcriptional activator
Line 107: Line 113:
*MtaN transcriptional activator
*MtaN transcriptional activator
-
**[[1r8d]] – BsTA <br />
+
**[[1r8d]], [[1jbg]] – BsTA N-terminal <br />
 +
**[[4p54]] – TA (mutant) - ''Helicobacter pylori'' <br />
*RfaH transcriptional activator
*RfaH transcriptional activator
Line 113: Line 120:
**[[2oug]] – EcTA <br />
**[[2oug]] – EcTA <br />
**[[2lcl]] – EcTA C terminal - NMR<br />
**[[2lcl]] – EcTA C terminal - NMR<br />
 +
**[[5ond]] – EcTA (mutant) + DNA <br />
*SoxR transcriptional activator
*SoxR transcriptional activator
Line 123: Line 131:
**[[3kos]] – CfTA effector binding domain – ''Citrobacter freundii''<br />
**[[3kos]] – CfTA effector binding domain – ''Citrobacter freundii''<br />
**[[3kot]] – CfTA effector binding domain (mutant)<br />
**[[3kot]] – CfTA effector binding domain (mutant)<br />
 +
**[[4wkm]] – CfTA effector binding domain + peptide<br />
 +
**[[5mmh]] – PaTA effector binding domain<br />
*GlxR transcriptional activator
*GlxR transcriptional activator
-
**[[3r6s]] – TA +cAMP – ''Corynebacterium glutamicum'' <br />
+
**[[4byy]] – CgTA – ''Corynebacterium glutamicum'' <br />
 +
**[[3r6s]], [[4cyd]] – CgTA + cAMP <br />
*OxyR transcriptional activator
*OxyR transcriptional activator
**[[3t22]], [[3ho7]], [[3uki]] – TA regulatory domain – ''Porphyromonas gingivalis'' <br />
**[[3t22]], [[3ho7]], [[3uki]] – TA regulatory domain – ''Porphyromonas gingivalis'' <br />
 +
**[[3jvt]] – TA – ''Neiserria meningitidis'' <br />
 +
**[[4x6g]] – PaTA (mutant) <br />
 +
**[[4y0m]] – PaTA regulatory domain <br />
 +
**[[4xws]] – PaTA regulatory domain (mutant) <br />
 +
**[[5x0v]] – VvTA-2 regulatory domain - ''Vibrio vulnificus'' <br />
 +
**[[5x0q]], [[5b70]], [[5b7d]], [[5b7h]] – VvTA-2 regulatory domain (mutant)<br />
*PlcR transcriptional activator
*PlcR transcriptional activator
**[[4fsc]] – BtTA - ''Bacillus thuringiensis'' <br />
**[[4fsc]] – BtTA - ''Bacillus thuringiensis'' <br />
 +
**[[2qfc]] – BtTA + PAPR peptide <br />
**[[3u3w]] – BtTA + DNA + PAPR peptide <br />
**[[3u3w]] – BtTA + DNA + PAPR peptide <br />
Line 154: Line 172:
**[[4k2e]], [[4ooi]] – TA - ''Vibrio cholerae''<br />
**[[4k2e]], [[4ooi]] – TA - ''Vibrio cholerae''<br />
 +
**[[3jth]] – VvTA <br />
*Aft2 transcriptional activator
*Aft2 transcriptional activator

Revision as of 21:57, 26 September 2018

Structure of transcriptional activator C-Myb DNA-binding domain (deeppink) complex with DNA, CAAT/enhancer binding protein β (cyan and green) and K+ ion (purple) (PDB entry 1h89)

Drag the structure with the mouse to rotate

3D Structures of transcriptional activator

Updated on 26-September-2018

References

  1. ↑ Titz B, Thomas S, Rajagopala SV, Chiba T, Ito T, Uetz P. Transcriptional activators in yeast. Nucleic Acids Res. 2006 Feb 7;34(3):955-67. Print 2006. PMID:16464826 doi:http://dx.doi.org/34/3/955

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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