Trehalulose synthase

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== Structural highlights ==
== Structural highlights ==
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<scene name='59/597011/Cv/3'>THS binds sucrose</scene> in a <scene name='59/597011/Cv/4'>deep pocket</scene> with mostly conserved residues<ref>PMID:17597061</ref>.
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<scene name='59/597011/Cv/5'>THS binds sucrose</scene> (water molecules are shown as red spheres) in a <scene name='59/597011/Cv/6'>deep pocket</scene> with mostly conserved residues<ref>PMID:17597061</ref>.
</StructureSection>
</StructureSection>

Revision as of 14:00, 26 September 2019

Structure of trehalulose synthase complex with sucrose and Ca+2 ion (green) (PDB code 2pwe).

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3D structures of trehalulose synthase

Updated on 26-September-2019

References

  1. Thevelein JM, Hohmann S. Trehalose synthase: guard to the gate of glycolysis in yeast? Trends Biochem Sci. 1995 Jan;20(1):3-10. PMID:7878741
  2. Venables MC, Brouns F, Jeukendrup AE. Oxidation of maltose and trehalose during prolonged moderate-intensity exercise. Med Sci Sports Exerc. 2008 Sep;40(9):1653-9. doi: 10.1249/MSS.0b013e318175716c. PMID:18685525 doi:http://dx.doi.org/10.1249/MSS.0b013e318175716c
  3. Ravaud S, Robert X, Watzlawick H, Haser R, Mattes R, Aghajari N. Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization. J Biol Chem. 2007 Sep 21;282(38):28126-36. Epub 2007 Jun 27. PMID:17597061 doi:10.1074/jbc.M704515200

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Michal Harel, Alexander Berchansky

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