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6d6n

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Current revision (14:33, 29 November 2023) (edit) (undo)
 
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==The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 16==
==The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 16==
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<StructureSection load='6d6n' size='340' side='right' caption='[[6d6n]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
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<StructureSection load='6d6n' size='340' side='right'caption='[[6d6n]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6d6n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D6N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D6N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6d6n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D6N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6D6N FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FXJ:2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl)amino]methyl}phenyl+4-methoxybenzoate'>FXJ</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6d6b|6d6b]], [[6d6c|6d6c]], [[6d6d|6d6d]], [[6d6l|6d6l]], [[6d6m|6d6m]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FXJ:2,4-dibromo-6-{[(2-nitrobenzene-1-carbonyl)amino]methyl}phenyl+4-methoxybenzoate'>FXJ</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lasR, PA1430 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6d6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d6n OCA], [https://pdbe.org/6d6n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6d6n RCSB], [https://www.ebi.ac.uk/pdbsum/6d6n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6d6n ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d6n OCA], [http://pdbe.org/6d6n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d6n RCSB], [http://www.ebi.ac.uk/pdbsum/6d6n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d6n ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LASR_PSEAE LASR_PSEAE]] Transcriptional activator of elastase structural gene (LasB). Binds to the PAI autoinducer.
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[https://www.uniprot.org/uniprot/LASR_PSEAE LASR_PSEAE] Transcriptional activator of elastase structural gene (LasB). Binds to the PAI autoinducer.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Transcriptional activator|Transcriptional activator]]
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pseae]]
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[[Category: Large Structures]]
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[[Category: Dong, S H]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Nair, S K]]
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[[Category: Dong SH]]
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[[Category: Luxr receptor]]
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[[Category: Nair SK]]
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[[Category: Signaling protein-agonist complex]]
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Current revision

The structure of ligand binding domain of LasR in complex with TP-1 homolog, compound 16

PDB ID 6d6n

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