2xcf
From Proteopedia
(Difference between revisions)
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==Crystal structure of HCV NS3 protease with a boronate inhibitor== | ==Crystal structure of HCV NS3 protease with a boronate inhibitor== | ||
| - | <StructureSection load='2xcf' size='340' side='right' caption='[[2xcf]], [[Resolution|resolution]] 2.48Å' scene=''> | + | <StructureSection load='2xcf' size='340' side='right'caption='[[2xcf]], [[Resolution|resolution]] 2.48Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xcf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XCF OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[2xcf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XCF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XCF FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BBQ:CYCLOPENTYL+N-[(2S)-1-[(2S,4R)-2-[[(4R)-8-HYDROXY-1,6,10-TRIOXA-5$L^{4}-BORASPIRO[4.5]DECAN-4-YL]CARBAMOYL]-4-ISOQUINOLIN-1-YLOXY-PYRROLIDIN-1-YL]-3,3-DIMETHYL-1-OXO-BUTAN-2-YL]CARBAMATE'>BBQ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BBQ:CYCLOPENTYL+N-[(2S)-1-[(2S,4R)-2-[[(4R)-8-HYDROXY-1,6,10-TRIOXA-5$L^{4}-BORASPIRO[4.5]DECAN-4-YL]CARBAMOYL]-4-ISOQUINOLIN-1-YLOXY-PYRROLIDIN-1-YL]-3,3-DIMETHYL-1-OXO-BUTAN-2-YL]CARBAMATE'>BBQ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xcf OCA], [http://pdbe.org/2xcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xcf RCSB], [http://www.ebi.ac.uk/pdbsum/2xcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xcf ProSAT]</span></td></tr> |
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Baker, S J]] | [[Category: Baker, S J]] | ||
[[Category: Ding, C Z]] | [[Category: Ding, C Z]] | ||
Revision as of 08:01, 4 November 2020
Crystal structure of HCV NS3 protease with a boronate inhibitor
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Categories: Large Structures | Baker, S J | Ding, C Z | Edge, C M | Ellis, M | Fan, D | Grimes, R M | Hubbard, J A | Jarvest, R L | Kazmierski, W M | Lazarides, L X | Li, Q | Li, X | Liao, L | Liu, Y | McDowell, B | Mordaunt, J E | Nassau, P | Ni, Z J | Pennicott, L E | Plattner, J J | Qian, X | Rowland, P | Skarzynski, T J | Slater, M J | Smith, G K | Somers, D O | Thommes, P | White, G V | Wright, J | Wright, L L | Zhang, Y K | Zhou, Y | Zou, W | Boronate inhibitor | Hydrolase | Protease | Viral reproduction
