2qsk
From Proteopedia
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'''Atomic-resolution crystal structure of the Recombinant form of Scytovirin''' | '''Atomic-resolution crystal structure of the Recombinant form of Scytovirin''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QSK OCA]. | |
==Reference== | ==Reference== | ||
Atomic-resolution crystal structure of the antiviral lectin scytovirin., Moulaei T, Botos I, Ziolkowska NE, Bokesch HR, Krumpe LR, McKee TC, O'Keefe BR, Dauter Z, Wlodawer A, Protein Sci. 2007 Dec;16(12):2756-60. Epub 2007 Oct 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17965185 17965185] | Atomic-resolution crystal structure of the antiviral lectin scytovirin., Moulaei T, Botos I, Ziolkowska NE, Bokesch HR, Krumpe LR, McKee TC, O'Keefe BR, Dauter Z, Wlodawer A, Protein Sci. 2007 Dec;16(12):2756-60. Epub 2007 Oct 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17965185 17965185] | ||
| - | [[Category: Protein complex]] | ||
| - | [[Category: Scytonema varium]] | ||
[[Category: Botos, I.]] | [[Category: Botos, I.]] | ||
[[Category: Dauter, Z.]] | [[Category: Dauter, Z.]] | ||
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[[Category: Wlodawer, A.]] | [[Category: Wlodawer, A.]] | ||
[[Category: Ziolkowska, N E.]] | [[Category: Ziolkowska, N E.]] | ||
| - | [[Category: | + | [[Category: Lectin]] |
| - | [[Category: | + | [[Category: Sugar binding protein]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 15:35:46 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 12:35, 4 May 2008
Atomic-resolution crystal structure of the Recombinant form of Scytovirin
Overview
The crystal structures of the natural and recombinant antiviral lectin scytovirin (SVN) were solved by single-wavelength anomalous scattering and refined with data extending to 1.3 A and 1.0 A resolution, respectively. A molecule of SVN consists of a single chain 95 amino acids long, with an almost perfect sequence repeat that creates two very similar domains (RMS deviation 0.25 A for 40 pairs of Calpha atoms). The crystal structure differs significantly from a previously published NMR structure of the same protein, with the RMS deviations calculated separately for the N- and C-terminal domains of 5.3 A and 3.7 A, respectively, and a very different relationship between the two domains. In addition, the disulfide bonding pattern of the crystal structures differs from that described in the previously published mass spectrometry and NMR studies.
About this Structure
Full crystallographic information is available from OCA.
Reference
Atomic-resolution crystal structure of the antiviral lectin scytovirin., Moulaei T, Botos I, Ziolkowska NE, Bokesch HR, Krumpe LR, McKee TC, O'Keefe BR, Dauter Z, Wlodawer A, Protein Sci. 2007 Dec;16(12):2756-60. Epub 2007 Oct 26. PMID:17965185 Page seeded by OCA on Sun May 4 15:35:46 2008
