Urea transporter
From Proteopedia
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- | To help give a better idea of how the urea transporter is oriented in the membrane lipid bilayer, <scene name='Urea_transporter/Opm_3k3f/3'>a slab representative of hydrophobic core of the lipid bilayer</scene> as calculated by the [http://opm.phar.umich.edu/protein.php?pdbid=3kg2 Orientations of Proteins in Membranes database](University of Michigan, USA) is shown with the red patch of spheres indicating the boundary of the hydrophobic core closet to the outside of the cell and the dark blue patch of spheres indicating the boundary closest to the inside of the cell. | + | To help give a better idea of how the '''urea transporter''' is oriented in the membrane lipid bilayer, <scene name='Urea_transporter/Opm_3k3f/3'>a slab representative of hydrophobic core of the lipid bilayer</scene> as calculated by the [http://opm.phar.umich.edu/protein.php?pdbid=3kg2 Orientations of Proteins in Membranes database](University of Michigan, USA) is shown with the red patch of spheres indicating the boundary of the hydrophobic core closet to the outside of the cell and the dark blue patch of spheres indicating the boundary closest to the inside of the cell. |
[[Image:Opm_periplasmic_topology.gif]] <!--I got this from Eric Martz's [[Mechanosensitive channels: opening and closing]]--> | [[Image:Opm_periplasmic_topology.gif]] <!--I got this from Eric Martz's [[Mechanosensitive channels: opening and closing]]--> | ||
Revision as of 21:54, 4 October 2018
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Contents |
3D structures of urea transporter
Update February 2013
3k3f, 3me1 – DvUT – Desulfovibrio vulgaris
3m6e – DvUT (mutant)
3k3g – DvUT + dimethylurea
4ezc – bUT + ceramide - bovine
4ezd – bUT + ceramide + selenourea
Reference for the structure
- Levin EJ, Quick M, Zhou M. Crystal structure of a bacterial homologue of the kidney urea transporter. Nature. 2009 Dec 10;462(7274):757-61. Epub . PMID:19865084 doi:10.1038/nature08558
See Also
- Knepper MA, Mindell JA. Structural biology: Molecular coin slots for urea. Nature. 2009 Dec 10;462(7274):733-4. PMID:20010678 doi:10.1038/462733a
- For Additional Information, See Membrane Channels & Pumps
Reference
Page started with original page on 3k3f seeded by OCA on Thu Jan 28 14:58:46 2010
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Wayne Decatur, David Canner, Jaime Prilusky, Joel L. Sussman
Categories: Desulfovibrio vulgaris str. hildenborough | Levin, E J. | NYCOMPS, New York Consortium on Membrane Protein Structure. | Zhou, M. | Channel | Membrane protein | New york consortium on membrane protein structure | Nycomp | Protein structure initiative | Psi-2 | Structural genomic | Transport protein | Transporter | Urea transport | Topic Page