6bo4

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'''Unreleased structure'''
 
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The entry 6bo4 is ON HOLD until Paper Publication
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==Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domain==
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<StructureSection load='6bo4' size='340' side='right' caption='[[6bo4]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6bo4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BO4 FirstGlance]. <br>
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Description:
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bo5|6bo5]]</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bo4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bo4 OCA], [http://pdbe.org/6bo4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bo4 RCSB], [http://www.ebi.ac.uk/pdbsum/6bo4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bo4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/TRPV2_RAT TRPV2_RAT]] Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH (By similarity).<ref>PMID:10201375</ref> <ref>PMID:15249591</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Dosey, T L]]
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[[Category: Wang, Z]]
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[[Category: Cation]]
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[[Category: Channel]]
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[[Category: Membrane protein]]
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[[Category: Open]]
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[[Category: Trp]]

Revision as of 06:32, 5 December 2018

Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domain

6bo4, resolution 4.00Å

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