This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6bo4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6bo4 is ON HOLD until Paper Publication
+
==Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domain==
-
 
+
<StructureSection load='6bo4' size='340' side='right' caption='[[6bo4]], [[Resolution|resolution]] 4.00&Aring;' scene=''>
-
Authors:
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6bo4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BO4 FirstGlance]. <br>
-
Description:
+
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6bo5|6bo5]]</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bo4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bo4 OCA], [http://pdbe.org/6bo4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bo4 RCSB], [http://www.ebi.ac.uk/pdbsum/6bo4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bo4 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/TRPV2_RAT TRPV2_RAT]] Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH (By similarity).<ref>PMID:10201375</ref> <ref>PMID:15249591</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Dosey, T L]]
 +
[[Category: Wang, Z]]
 +
[[Category: Cation]]
 +
[[Category: Channel]]
 +
[[Category: Membrane protein]]
 +
[[Category: Open]]
 +
[[Category: Trp]]

Revision as of 06:32, 5 December 2018

Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domain

6bo4, resolution 4.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6bo4"
Personal tools