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2z2o
From Proteopedia
(Difference between revisions)
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==Crystal Structure of apo virginiamycin B lyase from Staphylococcus aureus== | ==Crystal Structure of apo virginiamycin B lyase from Staphylococcus aureus== | ||
| - | <StructureSection load='2z2o' size='340' side='right' caption='[[2z2o]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='2z2o' size='340' side='right'caption='[[2z2o]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2z2o]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2z2o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z2O FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2z2n|2z2n]], [[2z2p|2z2p]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2z2n|2z2n]], [[2z2p|2z2p]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vgb, vgh ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vgb, vgh ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z2o OCA], [https://pdbe.org/2z2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z2o RCSB], [https://www.ebi.ac.uk/pdbsum/2z2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z2o ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/VGB_STAAU VGB_STAAU]] Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.<ref>PMID:11467949</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Berghuis, A M]] | [[Category: Berghuis, A M]] | ||
[[Category: Korczynska, M]] | [[Category: Korczynska, M]] | ||
Revision as of 10:44, 8 December 2021
Crystal Structure of apo virginiamycin B lyase from Staphylococcus aureus
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