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2yqd

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==Solution structure of the fifth bromodomain from mouse polybromo-1==
==Solution structure of the fifth bromodomain from mouse polybromo-1==
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<StructureSection load='2yqd' size='340' side='right' caption='[[2yqd]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2yqd' size='340' side='right'caption='[[2yqd]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yqd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YQD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yqd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YQD FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pb1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pb1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqd OCA], [http://pdbe.org/2yqd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yqd RCSB], [http://www.ebi.ac.uk/pdbsum/2yqd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqd ProSAT], [http://www.topsan.org/Proteins/RSGI/2yqd TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yqd OCA], [https://pdbe.org/2yqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yqd RCSB], [https://www.ebi.ac.uk/pdbsum/2yqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yqd ProSAT], [https://www.topsan.org/Proteins/RSGI/2yqd TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PB1_MOUSE PB1_MOUSE]] Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) (By similarity). Acts as a negative regulator of cell proliferation (By similarity).
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[[https://www.uniprot.org/uniprot/PB1_MOUSE PB1_MOUSE]] Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) (By similarity). Acts as a negative regulator of cell proliferation (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
[[Category: Hayashi, F]]
[[Category: Hayashi, F]]

Revision as of 07:10, 10 November 2021

Solution structure of the fifth bromodomain from mouse polybromo-1

PDB ID 2yqd

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