2zov

From Proteopedia

(Difference between revisions)

Revision as of 12:07, 29 July 2020

Structure of the periplasmic domain of MotB from Salmonella (crystal form I)

Structural highlights

2zov is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Related:	2zvy, 2zvz
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[MOTB_SALTY] MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Torque generation in the Salmonella flagellar motor is coupled to translocation of H(+) ions through the proton-conducting channel of the Mot protein stator complex. The Mot complex is believed to be anchored to the peptidoglycan (PG) layer by the putative peptidoglycan-binding (PGB) domain of MotB. Proton translocation is activated only when the stator is installed into the motor. We report the crystal structure of a C-terminal periplasmic fragment of MotB (MotB(C)) that contains the PGB domain and includes the entire periplasmic region essential for motility. Structural and functional analyses indicate that the PGB domains must dimerize in order to form the proton-conducting channel. Drastic conformational changes in the N-terminal portion of MotB(C) are required both for PG binding and the proton channel activation.

Stator assembly and activation mechanism of the flagellar motor by the periplasmic region of MotB.,Kojima S, Imada K, Sakuma M, Sudo Y, Kojima C, Minamino T, Homma M, Namba K Mol Microbiol. 2009 Aug;73(4):710-8. Epub 2009 Jul 21. PMID:19627504^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Kojima S, Imada K, Sakuma M, Sudo Y, Kojima C, Minamino T, Homma M, Namba K. Stator assembly and activation mechanism of the flagellar motor by the periplasmic region of MotB. Mol Microbiol. 2009 Aug;73(4):710-8. Epub 2009 Jul 21. PMID:19627504 doi:10.1111/j.1365-2958.2009.06802.x

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 See Also
6 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2zov"

@@ Line 1: / Line 1: @@
 ==Structure of the periplasmic domain of MotB from Salmonella (crystal form I)==
-<StructureSection load='2zov' size='340' side='right' caption='[[2zov]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+<StructureSection load='2zov' size='340' side='right'caption='[[2zov]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2zov]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZOV FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2zov]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ZOV FirstGlance]. <br>
 </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zvy|2zvy]], [[2zvz|2zvz]]</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zov OCA], [http://pdbe.org/2zov PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zov RCSB], [http://www.ebi.ac.uk/pdbsum/2zov PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zov ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2zov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zov OCA], [http://pdbe.org/2zov PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zov RCSB], [http://www.ebi.ac.uk/pdbsum/2zov PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zov ProSAT]</span></td></tr>
 </table>
 == Function ==
@@ Line 31: / Line 31: @@
 ==See Also==
-*[[Chemotaxis protein|Chemotaxis protein]]
+*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
+[[Category: Large Structures]]
 [[Category: Homma, M]]
 [[Category: Imada, K]]

2zov

From Proteopedia

Revision as of 12:07, 29 July 2020

Structure of the periplasmic domain of MotB from Salmonella (crystal form I)

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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