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<tr><td><div class="scrolling">'''Opening a Gate to Human Health'''<br>
<tr><td><div class="scrolling">'''Opening a Gate to Human Health'''<br>
''by Alice Clark'' (PDBe)<br>
''by Alice Clark'' (PDBe)<br>

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Opening a Gate to Human Health

by Alice Clark (PDBe)
In the 1970s, an exciting discovery of a family of medicines was made by the Japanese scientist Satoshi Ōmura. One of these molecules, ivermectin, is shown in this artwork bound in the ligand binding pocket of the Farnesoid X receptor, a protein which helps regulate cholesterol in humans. This structure showed that ivermectin induced transcriptional activity of FXR and could be used to regulate metabolism.

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